Similarly, S100A8 significantly reduced percentages of total and M-MDSC in spleens from mice with LLC cancers (Total MDSC: 1.10 ± 0.15% to 0.62 ± 0.10%, p < 0.05; M-MDSC: 0.18 ± 0.04% to 0.07 ± 0.01%, p < 0.05); PMN-MDSC showed a trend of decrease ( Figures 5J–L ).
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Intranasal Delivery of Recombinant S100A8 Protein Delays Lung Cancer Growth by Remodeling the Lung Immune Microenvironment.
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