The PCOS GWAS Candidate Gene ZNF217 Influences Theca Cell Expression of DENND1A.V2, CYP17A1, and Androgen Production.

J Endocr Soc · 2022 · PMC9155636 · PMID 35668995

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did not reach statistical significanceno p-value reported

Although it did not reach statistical significance, ZNF217 in forskolin-stimulated PCOS theca cells trended toward lower expression as compared to normal theca cells (see Fig. 2C ).

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The PCOS GWAS Candidate Gene <i>ZNF217</i> Influences Theca Cell Expression of <i>DENND1A.V2</i>, <i>CYP17A1</i>, and Androgen Production.

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