It is apparent from Figure 5(a-c) that there was a clear trend of increasing in the levels of inflammatory cytokines TNF-α, IL-6 and IL-1β after DOX induction in H9c2 cells, whereas propofol decreased the levels of TNF-α, IL-6 and IL-1β.
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Propofol protects cardiomyocytes from doxorubicin-induced toxic injury by activating the nuclear factor erythroid 2-related factor 2/glutathione peroxidase 4 signaling pathways.
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