High nerve density in breast cancer is associated with poor patient outcome.

FASEB Bioadv · 2022 · PMC9164247 · PMID 35664834

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3.4 High nerve trunk density is associated with poor patient PFS and OS in breast cancer While there was a clear trend between nerve fibers and patient outcomes (Figure 5 ), analyses stratified by nerve trunks alone indicated their presence was significantly related to patient PFS (HR = 2.755, 95% CI = 1.395 to 5.439, p = 0.0258) and OS (HR = 3.845, 95% CI = 1.528 to 9.674, p = 0.0494) (Figure 6A,B ).

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