15th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT)

Assessment of antibiotic prescription patterns in the pulmonology department based on classification AWaRe 2021 and WHO Model List of Essential Medicines (EML) 2021 (22nd edition) revealed a negative trend in the use of the most costly group (A) of antibiotics with a low level of evidence of efficiency or safety in pulmonology: Doripenem, Ertapenem, Levofloxacin, Cefepime.

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Otherwise, a trend was noted with respect to OPRM1 A118G and intra-operative remifentanil consumption, while a marginally significant association has emerged between the strongest systolic pressure (SP) reduction, at the time of surgical cut, and OPRM1 A118G, with GG genotypes displaying consuming less remifentanil and greater SP reduction (p = 0.079 and 0.043, respectively).

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