DNA methylation clocks for dogs and humans.

Proc Natl Acad Sci U S A · 2022 · PMC9173771 · PMID 35580182

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closest p · 0.2× alpha

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nominally significantP = 0.01actually significant

We observed a nominally significant overlap ( P = 0.01) between genes implicated by the EWAS of dog breed lifespan with those implicated by GWAS of human parental lifespan, based on the following shared genes: TUBG1 , FAM134C , BCL11A , PRPF40B , HIPK1 , DYNLRB2 , FIGN , PGS1 , and TOX ( Dataset S5 ).

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