Inhibition of D-2HG leads to upregulation of a proinflammatory gene signature in a novel HLA-A2/HLA-DR1 transgenic mouse model of IDH1R132H-expressing glioma.

J Immunother Cancer · 2022 · PMC9174833 · PMID 35606087

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did not reach statistical significanceno p-value reported

Treatment with AG-881 alone prolonged survival (MS=24 days), although the difference did not reach statistical significance due to the small cohort size.

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