URMC-099 prophylaxis prevents hippocampal vascular vulnerability and synaptic damage in an orthopedic model of delirium superimposed on dementia.

FASEB J · 2022 · PMC9175136 · PMID 35535564

Europe PMC DOI

hedged sentences

0.0511

closest p · 1.0× alpha

0.1860

boldest claim

The sentences

a negative trendp = .0511so close (0.05 < p ≤ 0.1)

a positive trendp = .0511so close (0.05 < p ≤ 0.1)

After surgery, we found there is a positive trend of Iba1 expression along with a negative trend in surface area compared to sham ( p = .0511 and p = .0921, respectively; Figure 6C,D ).

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failed to reach significancep = .186not close (p > 0.1)

Additionally, it also reduced the basal immunoreactivity of PECAM‐1 by 24% after IL‐1β stimulation but failed to reach significance ( p = .186; Figure 1A,C ).

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