Barely Significant
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Cryoprecipitate as an alternative to platelet transfusion in thrombocytopenia.

EJHaem · 2022 · PMC9175722 · PMID 35846213

Europe PMCDOI
1
hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)
Levels of sGPVI (the soluble ectodomain of GPVI released from activated platelets by metalloproteolysis) in plasma pretransfusion fell within normal ranges observed in healthy donors [ 20 ], and showed a mean increase of 3.7 ng/ml from pretransfusion levels following cryoprecipitate transfusion ( p = 0.002) and a smaller increment following subsequent platelet transfusion, which did not reach statistical significance ( p = 0.06, Figure 3 ). sGPVI was subsequently measured in four apheresis cryoprecipitate units, showing a mean of 32.1 ng/ml.

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