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A mutant fibrinogen that is unable to form fibrin can improve renal phenotype in mice with sickle cell anemia.

EJHaem · 2021 · PMC9176143 · PMID 35844706

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showed a trendno p-value reported
WBC, neutrophils, and lymphocytes showed a trend toward higher counts in SS Fib WT mice compared with the BoyJ Fib WT mice, whereas platelet counts were decreased in SS mice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.