PVP-Modified Multifunctional Bi₂WO₆ Nanosheets for Enhanced CT Imaging and Cancer Radiotherapy.

After subcutaneously inoculating mice with CAL27 cells to establish the tumor models, the mice were randomly divided into four groups: (I) control group, (II) PVP–Bi 2 WO 6 group, (III) X-ray irradiation group, and (IV) PVP–Bi 2 WO 6 + X-ray irradiation group. In the exploration of the optimal time to apply radiation, the experimental results showed that the accumulation rate of PVP–Bi 2 WO 6 NSs in CAL27 tumors showed a trend of gradually increasing at first and then gradually decreasing, and it reached the highest value at 24 h, which was 6.19% ( Figure S2 ).

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