Oncogenic KRAS-Induced Protein Signature in the Tumor Secretome Identifies Laminin-C2 and Pentraxin-3 as Useful Biomarkers for the Early Diagnosis of Pancreatic Cancer.

Cancers (Basel) · 2022 · PMC9179463 · PMID 35681634

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

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boldest claim

The sentences

a trend approaching significancep = 0.08so close (0.05 < p ≤ 0.1)

Of the seven selected genes, LAMC2, FPPS, TNC, RAN and STC2 had significantly higher mRNA levels in PDAC samples compared to the normal adjacent pancreatic tissues, and PTX3 showed a trend approaching significance ( p = 0.08), while RNA levels of UCHL-1 were not significantly increased in tumor tissues.

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