Barely Significant
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High Expression of a Cancer Stemness-Related Gene, Chromobox 8 (CBX8), in Normal Tissue Adjacent to the Tumor (NAT) Is Associated with Poor Prognosis of Colorectal Cancer Patients.

Cells · 2022 · PMC9180723 · PMID 35681547

2
hedged sentences
0.0750
closest p · 1.5× alpha
0.0750
boldest claim

The sentences

a positive trendp = 0.075so close (0.05 < p ≤ 0.1)
Moreover, NAT CBX8 gene level showed a positive trend with post-operative CEA (R = 0.233, p = 0.075, Figure 3 C), which is a risk factor for recurrence [ 26 , 27 , 28 , 29 ].

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showed a trendno p-value reported
In addition, our data revealed that higher tumor CBX8 showed a trend towards lower tumor invasion.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.