Diagnostic accuracy of magnetic resonance imaging targeted biopsy techniques compared to transrectal ultrasound guided biopsy of the prostate: a systematic review and meta-analysis.

Prostate Cancer Prostatic Dis · 2022 · PMC9184263 · PMID 34548624

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

The analysis also found the pooled relative CDR in detecting csPCa trended towards higher in patients that had at least one prior negative biopsy (1.59 [95% CI 1.16-2.16]) compared to biopsy-naive men (1.06 [95% CI 0.94–1.20]) although this did not reach statistical significance ( p = 0.06).

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highly significantno p-value reported

Heterogeneity was highly significant––83.7% for MRI-GB and 97.7% for TRUS-GB.

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