Despite not all the aforementioned differences between TD + placebo and normal T men achieving statistical significance, a clear trend was well recognizable for most of these (Fig. 2 ).
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Testosterone does not affect lower urinary tract symptoms while improving markers of prostatitis in men with benign prostatic hyperplasia: a randomized clinical trial.
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In the TD + TTh group, the expression of IP-10 was significantly reduced below that of men with normal T and a trend towards significance was found for MCP-1 (Fig. 2 , Panels B and D).