T cell repertoire in peripheral blood as a potential biomarker for predicting response to concurrent cetuximab and nivolumab in head and neck squamous cell carcinoma.

An overall trend toward favorable patient survival was also observed in the polyclonal group.

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The overall TCR diversity curves in the CR/PR group remained stable in the first two time points but showed a trend toward decreased TCR diversity (represented by decreased total arrangements) towards the end of treatment (around C4D1) in multiple patients, suggesting a potential key time point for future patient monitoring.

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