Amygdala-pons connectivity is hyperactive and associated with symptom severity in depression.

Although the extracted dGCM demonstrated a negative trend, indicating that other ROIs have dominant influences on the pons, no other values survived multiple comparisons.

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The correlation with the number of depressive episodes (r[49] = 0.28, p = 0.05) could be considered marginally significant.

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We observed a positive trend in the extracted dGCM, even though not all ROIs were significant after correcting for multiple comparisons.

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