Reduced Bone Mass in Collagen Prolyl 4-Hydroxylase <i>P4ha1</i> ^+/-; <i>P4ha2</i> ^-/- Compound Mutant Mice.

At 6 weeks of age, trabecular bone volume fraction (BV/TV) follows a decreasing trend in the distal P4ha1 +/− ; P4ha2 −/− femur versus the P4ha2 +/− control (not statistically significant, p = 0.109, Supplemental Fig.

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Double‐labeled surface (dLS) followed a decreasing trend whereby dLS in the P4ha1 +/− ; P4ha2 −/− samples was half of that in the P4ha2 +/− control mice, but the difference did not reach statistical significance (Supplemental Fig.

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