Independent validation of stromal uPA in ABCSG-08: Level 1b evidence for the prognostic value of uPA immunohistochemistry.

Breast · 2022 · PMC9190055 · PMID 35689881

Europe PMC DOI

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0.1610

closest p · 3.2× alpha

0.1610

boldest claim

The sentences

showed a trendp=0.161not close (p > 0.1)

In multivariate analyses, the expression of stromal uPA remained significantly associated with prolonged DRFS (adjusted HR for distant relapse 2.78; 95% CI 1.31–5.93; p=0.008 Cox regression analysis) and again showed a trend towards an improved OS (adjusted HR for death 1.47; 95% CI 0.86–2.50; p=0.161 ) when compared to women whose tumors did not express uPA ( Table 2 ).

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