cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model.

iScience · 2022 · PMC9194172 · PMID 35712074

Europe PMC DOI

hedged sentence

0.4260

closest p · 8.5× alpha

0.4260

boldest claim

The sentences

did not reach statistical significancep = 0.426not close (p > 0.1)

Consistently, the onset of the disease in SOD1-G93A mice also showed a marginal improvement after treatment with RU.521, and C-176; although this difference did not reach statistical significance (logrank test for survival plot: p = 0.426 for C-176; p = 0.0728 for RU.521) ( Figure 4 I).

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