In the subgroup analysis, both patients who were treated with dupilumab or omalizumab were significantly less likely to experience asthma exacerbation than those treated with placebo]RR 0.27, 95% CI 0.13–0.57; OR 0.31, 95% CI 0.12–0.78, Figure 1B ]; whereas the decreased incidence in patients who received mepolizumab failed to reach statistical significance ( P = 0.79) (RR 0.82, 95% CI 0.18–3.66).
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