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Sequential or Simultaneous Injection of Preformed Fibrils and AAV Overexpression of Alpha-Synuclein Are Equipotent in Producing Relevant Pathology and Behavioral Deficits.

J Parkinsons Dis · 2022 · PMC9198765 · PMID 35213388

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Although the TH + loss in the three AAV-GFP groups seemed to be higher compared to the loss observed in the three AAV-h-αSyn groups, the comparison between counts in the ipsilateral side did not reach statistical significance ( Sidak , all n.s.).

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