Sex-Specific Associations Between Serum Lipids, Antinuclear Antibodies, and Statin Use in National Health and Nutrition Examination Surveys 1999-2004.

Front Med (Lausanne) · 2022 · PMC9198832 · PMID 35721098

Europe PMC DOI

hedged sentences

0.0680

closest p · 1.4× alpha

0.0680

boldest claim

The sentences

a statistical trendP = 0.068so close (0.05 < p ≤ 0.1)

When comparing the distribution of clinical lipid ranges by sex and ANA status, we observed significant differences in total cholesterol and HDL-C, in addition to a statistical trend in LDL-C distributions ( P = 0.068) and no group differences in clinical triglyceride range distributions.

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did not reach statistical significanceno p-value reported

Further, while overall sex-specific differences in the distribution of race/ethnicity or education level across ANA+ and ANA– groups did not reach statistical significance, it is important to note that Black men and women represented a greater proportion of ANA+ individuals as compared to ANA– groups (Men: 26.7% ANA+ vs. 16.1% ANA–; Women: 18.4% ANA+ vs. 15.8% ANA–), and that a greater percentage of Hispanic men were ANA– (14.5%) as compared to women (10.0%), suggesting that sex may differentially impact autoimmune risk across racial/ethnic groups.

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