Enduring disruption of reward and stress circuit activities by early-life adversity in male rats.

Transl Psychiatry · 2022 · PMC9200783 · PMID 35705547

Europe PMC DOI

hedged sentences

0.0596

closest p · 1.2× alpha

0.1007

boldest claim

The sentences

near-significantP = 0.0596so close (0.05 < p ≤ 0.1)

In BLA, opioid-experienced rats showed a near-significant increase in heroin-induced Fos relative to naïve rats (5B; main effect of opioid experience: F (1,25) = 3.893, P = 0.0596; η p 2 = 0.1347), with no main effect of rearing group (Fig. 5B ; F (1,25) = 0.6029, P = 0.4448 ) .

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a nonsignificant trendP = 0.1007not close (p > 0.1)

A nonsignificant trend towards an ELA × opioid experience interaction was also observed (Fig. 5B ; F (1,25) = 2.906, P = 0.1007; η p 2 = 0.1041).

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