Unlike the expression of mRNA, the expression of AMPK-ɑ and pAMPK-ɑ was also up-regulated when TNF-ɑ, IL-6, MMP1, and MMP3 showed a trend of up-regulation ( Figure 6D ).
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HAPLN1 Affects Cell Viability and Promotes the Pro-Inflammatory Phenotype of Fibroblast-Like Synoviocytes.
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The sentences
With highly significant changes observed in the expression of DEPs and DEGs, it is plausible to consider the involvement of HAPLN in a complex network of signaling pathways.