Timeline Kinetics of Systemic and Airway Immune Mediator Storm for Comprehensive Analysis of Disease Outcome in Critically Ill COVID-19 Patients.

Front Immunol · 2022 · PMC9204232 · PMID 35720401

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a clear trendno p-value reported

Data analysis demonstrated that a clear trend for a bimodal kinetics wave of serum soluble immune mediators in COVID patients, except for IL-1β, TNF and IL-5.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.