EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.

Nat Commun · 2022 · PMC9209511 · PMID 35725568

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showed a trendno p-value reported

This was in contrast to the immunosuppressive Tregs, which showed a trend towards decreased influx and proliferation in the ephrinB2 double knockout mice compared to the controls (Fig. 8a ).

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a trend towards significanceno p-value reported

We observed that the cohort with high EphB4 expression showed a trend towards significance and correlated with improved survival compared to the low EphB4 group (Hazard ratio: 0.7846; CI: 0.6024–1.022; p -value: 0.0691) (Fig. 9a ).

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