Myeloid DNA methyltransferase3b deficiency aggravates pulmonary fibrosis by enhancing profibrotic macrophage activation.

mRNA levels of Fn1 and Pdgfa were increased upon TGFB1 stimulation, which was further increased in DNMT3B deficient macrophages, although for Fn1 the difference between genotypes did not reach statistical significance (Fig. 1 B).

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