Sex Differences in Responses to Antidepressant Augmentations in Treatment-Resistant Depression.

However, no suicide or suicide attempts were reported during the study follow-up, underscoring that even if the pharmacological combinations did not lead to remission within 3 months, they may be significant in certain depressive domains such as preventing suicidal behaviors.

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Yet, a recent analysis by the Group for the Study of Resistant Depression showed a trend towards a more frequent administration of add-on treatments in men than in women ( Bartova et al. 2021 ).

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