Barely Significant
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Furfural Produces Dose-Dependent Attenuating Effects on Ethanol-Induced Toxicity in the Liver.

Front Pharmacol · 2022 · PMC9214037 · PMID 35754511

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showed a trendno p-value reported
IGFBP3, which can regulate IGF-1 function ( Annunziata et al., 2011 ), showed a trend opposite that of IGF-1 and IGF-1R.

also in 53,322 other papers

an increasing trendno p-value reported
There was no significant difference when the furfural dose was increased, but the NAD + /NADH ratio showed an increasing trend.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.