Barely Significant
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Mitonuclear genotype remodels the metabolic and microenvironmental landscape of Hürthle cell carcinoma.

Sci Adv · 2022 · PMC9216518 · PMID 35731870

Europe PMCDOI
1
hedged sentence
0.4000
closest p · 8.0× alpha
0.4000
boldest claim

The sentences

did not reach statistical significanceP = 0.4not close (p > 0.1)
Similarly, IHC analysis indicated that HWIDE tumors were depleted of CD8 + and CD4 + T cells relative to HMIN, although these results did not reach statistical significance (CD4 + T cells: mean HWIDE versus HMIN, 16 positive cells/high-power field (HPF) hotspot versus 52 positive cells/HPF hotspot, P = 0.4; CD8 + T cells: mean HWIDE versus HMIN, 26 positive cells/HPF hotspot versus 56 positive cells/HPF hotspot, P = 0.13; CD68 + cells: mean HWIDE versus HMIN, 43 positive cells/HPF hotspot versus 70 positive cells/HPF hotspot, P = 0.26, Fig. 3G ).

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