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Nanomaterials-Based Combinatorial Therapy as a Strategy to Combat Antibiotic Resistance.

Antibiotics (Basel) · 2022 · PMC9220075 · PMID 35740200

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a strong trendno p-value reported
There is a strong trend toward the rational design of drug combinations using direct targeting of small molecules and finding new targets or new mechanisms of antimicrobial action [ 19 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.