Early Forms of <i>α</i>-Synuclein Pathology Are Associated with Neuronal Complex I Deficiency in the Substantia Nigra of Individuals with Parkinson's Disease.

Biomolecules · 2022 · PMC9220830 · PMID 35740871

Europe PMC DOI

hedged sentences

0.1100

closest p · 2.2× alpha

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boldest claim

The sentences

did not reach statistical significancep = 0.11not close (p > 0.1)

However, this did not reach statistical significance when compared to LBs/PBs in CI-positive neurons in the post-hoc analysis (CI-positive: 23/176, 14%; CI-negative: 0/18, 0% p = 0.11).

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highly significantno p-value reported

In contrast, early α -syn aggregation shows a highly significant predilection for CI-negative over CI-positive neurons. 2.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.