Cortisol Regulates Cerebral Mitochondrial Oxidative Phosphorylation and Morphology of the Brain in a Region-Specific Manner in the Ovine Fetus.

In the cerebellum ( Figure 1 B), CI L and CI P respiratory rates were reduced following cortisol infusion; CI&CII P OXPHOS respiration also tended to be lower, but did not reach statistical significance ( p = 0.052).

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In the cerebellum ( Figure 2 B), but not the cortex ( Figure 2 A), the abundance of ANT1, a mitochondrial protein that facilitates the exchange of ADP and ATP across the mitochondrial inner membrane ( Figure 2 ), tended to be increased following cortisol infusion, although this failed to reach significance. 3.4.

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