Barely Significant
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Bone Turnover Marker (BTM) Changes after Denosumab in Giant Cell Tumors of Bone (GCTB): A Phase II Trial Correlative Study.

Cancers (Basel) · 2022 · PMC9220940 · PMID 35740530

2
hedged sentences
0.0512
closest p · 1.0× alpha
0.0512
boldest claim

The sentences

did not reach statistical significancep = 0.0512so close (0.05 < p ≤ 0.1)
Higher median ALP and s-CTX at baseline were observed in patients with tumor size ≥ 5 cm as compared with patients with tumor size < 5 cm but the differences did not reach statistical significance ( p = 0.0512 and p = 0.0589).

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an increasing trendno p-value reported
An increasing trend was observed for sPTH although not statistically significant ( Figure 3 ). 3.3.

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