miRNA-Mediated Knockdown of ATXN3 Alleviates Molecular Disease Hallmarks in a Mouse Model for Spinocerebellar Ataxia Type 3.

Nucleic Acid Ther · 2022 · PMC9221165 · PMID 34878314

Europe PMC DOI

hedged sentence

0.1900

closest p · 3.8× alpha

0.1900

boldest claim

The sentences

did not reach statistical significanceP = 0.19not close (p > 0.1)

Low-dose mi ATXN3 treatment resulted in an average lesion size that was half the size of PBS-treated animals, although this did not reach statistical significance ( P = 0.19).

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