EST79232 and EST79376, Two Novel Sigma-1 Receptor Ligands, Exert Neuroprotection on Models of Motoneuron Degeneration.

Int J Mol Sci · 2022 · PMC9223397 · PMID 35743175

Europe PMC DOI

hedged sentence

0.0810

closest p · 1.6× alpha

0.0810

boldest claim

The sentences

did not reach statistical significancep = 0.081so close (0.05 < p ≤ 0.1)

EST79232 and EST79376 caused a tendency to preserve NMJ innervation, although differences did not reach statistical significance when compared with the vehicle group ( p = 0.081 and p = 0.057, respectively) ( Figure 4 D–F).

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