HDM-specific serum IgG1 levels were increased in the HDM group compared to the PBS group, but they were decreased in the BPZE1 and BPZE1P groups compared to the HDM group, although this decrease did not reach statistical significance for the BPZE1P group (Fig. 1e ).
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Live attenuated pertussis vaccine for prevention and treatment of allergic airway inflammation in mice.
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Histological analyses showed that while in the BPZE1P 1 group there was no significant reduction in PAS-stained mucus compared to the non-vaccinated mice, a trend of decreased mucus secretion was seen in the BPZE1P 2 group, compared with the HDM group, which did not quite reach statistical significance.