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Safety and Tolerability of COVID-19 Vaccines in Patients with Cancer: A Single Center Retrospective Analysis.

Vaccines (Basel) · 2022 · PMC9227366 · PMID 35746500

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Risk Factors for Adverse Events In the multivariate logistic models, an age younger than 65 years [odds ratio (OR), 0.55; 95% CI, 0.32–0.94; p = 0.029] and female sex (OR, 1.84; 95% CI, 1.17–2.89; p = 0.008) were both considered significant risk factors for local adverse events after the first dose, but they did not reach statistical significance with regard to systemic adverse events after the first dose. mRNA vaccines were associated with higher risk of local adverse events after the second dose (OR, 0.19; 95% CI, 0.03–0.97; p = 0.046), although we only had 8/354 individuals with non-mRNA vaccines who underwent second vaccination dose, so our power was rather low for this particular conclusion.

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