Lower Inspiratory Breathing Depth Enhances Pulmonary Delivery Efficiency of ProAir Sprays.

Pharmaceuticals (Basel) · 2022 · PMC9227885 · PMID 35745624

Europe PMC DOI

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may not be significantno p-value reported

[ 14 ] are also different, even though they may not be significant contributors to their observed differences.

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a clear trendno p-value reported

Despite highly heterogenous DEF distributions, there is a clear trend that with increasing breathing depth, the local dose on the mouth roof increases (top view), while that on the ventral wall of the respiratory tract gradually decreases (bottom view).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.