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Increasing incidence rates of sexually transmitted infections from 2010 to 2019: an analysis of temporal trends by geographical regions and age groups from the 2019 Global Burden of Disease Study.

BMC Infect Dis · 2022 · PMC9233762 · PMID 35754034

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showed a trendno p-value reported
Conclusions Syphilis, chlamydia, trichomoniasis, and genital herpes showed a trend of increasing ASR from 2010 to 2019.

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an increasing trendno p-value reported
Globally, there was initially an increasing trend in the ASR of syphilis from 1990 to 2000.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.