Barely Significant
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Rapid early progression (REP) of glioblastoma is an independent negative prognostic factor: Results from a systematic review and meta-analysis.

Neurooncol Adv · 2022 · PMC9234755 · PMID 35769410

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did not reach statistical significanceP = .10so close (0.05 < p ≤ 0.1)
Studies with less than the median rate of GTR had a higher incidence rate of REP although differences did not reach statistical significance (OR 2.07, 95% CI 1.75–2.45, Chi-squared = 2.67, P = .10; Figure 4A ).

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