Budesonide/glycopyrronium/formoterol fumarate triple therapy prevents pulmonary hypertension in a COPD mouse model via NFκB inactivation.

However, the synergistic effect that dual or triple combination therapy had compared to single drug treatment groups are apparent, although it did not reach statistical significance in all phases experiments.

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Notably, there was a decreasing trend in their expression with the addition of formoterol and a further reduction with the addition of glycopyrronium.

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