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<i>Listeria</i>-Vectored Multiantigenic Tuberculosis Vaccine Enhances Protective Immunity against Aerosol Challenge with Virulent Mycobacterium tuberculosis in BCG-Immunized C57BL/6 and BALB/c Mice.

mBio · 2022 · PMC9239278 · PMID 35642945

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with BCG only, although the difference did not reach statistical significance for a single booster immunization (however, boosting twice with rLm4Ag plus rLm30 induced immunoprotection significantly more greatly than BCG alone in the lung [ P < 0.01]); (iii) immunity induced by M. tuberculosis 5Ag expressed from a single recombinant attenuated L. monocytogenes vaccine [rLm5A

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