Is it time to consider population screening for fracture risk in postmenopausal women? A position paper from the International Osteoporosis Foundation Epidemiology/Quality of Life Working Group.

Arch Osteoporos · 2022 · PMC9239944 · PMID 35763133

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

borderline significantp = 0.059so close (0.05 < p ≤ 0.1)

In contrast, in the per-protocol analysis 1, while no difference was observed in all incident fractures or MOF, a borderline significant reduction in hip fracture risk was observed in the screened group (169 vs 202 hip fractures, HR 0.82, 95%CI 0.67–1.01, p = 0.059).

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did not reach statistical significanceno p-value reported

The point estimate of the hazard ratio for other fracture outcomes, including osteoporotic fractures, major osteoporotic fractures and hip fractures was somewhat lower (0.91), but did not reach statistical significance.

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