In the phase II CAVALLI trial, R-CHOP combined with venetoclax in first-line therapy showed a trend for improved PFS and OS compared with patients with similar characteristics treated on the GOYA study with R-CHOP alone. 95 Mutations of enhancer of zeste homolog 2 ( EZH2 ) are a frequent genetic event in GCB DLBCLs.
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Current options and future perspectives in the treatment of patients with relapsed/refractory diffuse large B-cell lymphoma.
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