Deletion of Fmr1 in parvalbumin-expressing neurons results in dysregulated translation and selective behavioral deficits associated with fragile X syndrome.

Even though Fmr1 −/y -PV mice showed a trend for reduced platform crossings during the probe test, it did not reach significance (Fig. 3 E, p > 0.1, Student’s t test).

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In the social novelty portion of the 3CSI, there was an overall trend for WT-SOM and Fmr1 −/y -SOM mice to spend more time sniffing S2, however it was not significant (Additional file 1 : Fig.

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