At 1-week post-impact, both the 2 hits and 8 hits animals exhibited significantly decreased serum IL-6 compared with sham, while the 4 hits group approached significance in the same direction ( Figure 9B ).
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Titrating the Translational Relevance of a Low-Level Repetitive Head Impact Model.
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Hence, these changes could represent an overall trend toward anti-inflammation, or immune suppression.