19 Larger primary tumor size was found to be associated with a higher likelihood of neuraxis metastases, and likelihood of neuraxis metastases also trended toward a decrease in primary tumor heterogeneity based on texture features (although these results did not reach statistical significance). 19 In MB patients, Zheng et al. found a clinical-radiomic model to be predictive of preoperative Cerebrospinal Fluid (CSF) dissemination (as determined by head and spine MRI, as well as no subsequent dissemination at the 1-year follow-up for the non-CSF dissemination group). 33 Applications in Prognostication Tumor prognostication, both in terms of survival and risk of recurrence after treatment, is a topic of great interest within the field.
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