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The immune checkpoint ICOSLG is a relapse-predicting biomarker and therapeutic target in infant t(4;11) acute lymphoblastic leukemia.

iScience · 2022 · PMC9253708 · PMID 35800767

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Subsequent Kaplan-Meier analysis of all patients with the availabe outcome data (n = 43) demonstrated that the EFS disadvantage of patients with HOXA9 lo was quite modest and did not reach statistical significance in a log rank test ( Figure 3 B).

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